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使用口面部操作性疼痛测定法评估大鼠神经损伤诱导的机械超敏反应
JoVE Journal
Comportamento
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JoVE Journal Comportamento
Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
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使用口面部操作性疼痛测定法评估大鼠神经损伤诱导的机械超敏反应

2,984 Views

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07:39 min

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July 26, 2022

DOI:

10.3791/64221-v

DOI:
10.3791/64221-v

•

07:39 min
July 26, 2022

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1 Views
, , , , , ,
1Department of Oral and Maxillofacial Surgery,University of Florida, Gainesville, 2Department of Orthodontics,University of Florida, Gainesville, 3Stoelting Co. Wood Dale

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Orofacial Pain Assessment DeviceOPADOperant Reward Conflict ParadigmNociceptionLearningMotivationTranslational ValidityReflex-based AssaysInfraorbital NerveCCI SurgeryMechanical HypersensitivityRatPreclinical Pain ResearchAutomatedExperimenter BiasProtocol SetupApparatusEquipment ModesTesting StagesTreatment GroupsAnimal ID

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Donertas-Ayaz, B., Brice-Tutt, A. C., Malphurs, W. L., Montgomery, D., Mills, R. H., Neubert, J. K., Caudle, R. M. Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay. J. Vis. Exp. (185), e64221, doi:10.3791/64221 (2022).

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