Journal
/
Engenharia
/
Microfluidic Device for the Separation of Non-Metastatic (MCF-7) and Non-Tumor (MCF-10A) Breast Cancer Cells Using AC Dielectrophoresis
JoVE Journal
Engenharia
Author Produced
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Engenharia
Microfluidic Device for the Separation of Non-Metastatic (MCF-7) and Non-Tumor (MCF-10A) Breast Cancer Cells Using AC Dielectrophoresis

Microfluidic Device for the Separation of Non-Metastatic (MCF-7) and Non-Tumor (MCF-10A) Breast Cancer Cells Using AC Dielectrophoresis

2,092 Views

•

08:33 min

•

August 11, 2022

DOI:

10.3791/63850-v

DOI:
10.3791/63850-v

•

08:33 min
August 11, 2022

•

5 Views
, , ,
1Department of Biomedical Engineering,Foundation University Islamabad, 2College of Medical Technology,The Islamic University Najaf, 3Faculty of Mechanical Engineering,University of Tabriz, 4Department of Engineering Mathematics,University of Bristol, 5School of Life Sciences,University of Warwick

Summary

Automatically generated

Breast cancer cells exhibit different dielectric properties compared to non-tumor breast epithelial cells. It has been hypothesized that, based on this difference in dielectric properties, the two populations can be separated for immunotherapy purposes. To support this, we model a microfluidic device to sort MCF-7 and MCF-10A cells.

Explore More Videos

Microfluidic DeviceAC DielectrophoresisNon-metastatic Breast Cancer CellsNon-tumor Breast Epithelial CellsCell SeparationDielectric PropertiesMultiphysics SimulationParticle TracingFluid FlowElectric Field

Read Article

Cite this Article

ur Rehman, A., Zabibah, R. S., Kharratian, S., Mustafa, A. Microfluidic Device for the Separation of Non-Metastatic (MCF-7) and Non-Tumor (MCF-10A) Breast Cancer Cells Using AC Dielectrophoresis. J. Vis. Exp. (186), e63850, doi:10.3791/63850 (2022).

Download .ris file

Copy

Share Video

.

Copy