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Analyse du modèle murin de la maladie de Parkinson induit par des vecteurs viraux adéno-associés codant pour la α-synucléine humaine
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Neurociência
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JoVE Journal Neurociência
Analyzing the Parkinson’s Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein
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Analyse du modèle murin de la maladie de Parkinson induit par des vecteurs viraux adéno-associés codant pour la α-synucléine humaine

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14:45 min

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July 29, 2022

DOI:

10.3791/63313-v

DOI:
10.3791/63313-v

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14:45 min
July 29, 2022

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1 Views
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1Laboratorio de Neuroinmunología,Fundación Ciencia & Vida, 2Center for Integrative Biology,Universidad Mayor, 3FONDAP Geroscience Center for Brain Health and Metabolism, 4Buck Institute for Research on Ageing, 5Facultad de Medicina y Ciencia,Universidad San Sebastián

Tags

Parkinson’s DiseaseMouse ModelAdeno-associated Viral VectorsHuman α-synucleinStereotaxic DeliveryNigrostriatal PathwayNeurodegenerationNeuroinflammationMotor ImpairmentSynuclein PathologyMicroglial ActivationT-cell ActivationAseptic EnvironmentAnalgesiaAnesthesia

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Elgueta, D., Chovar, O., Ugalde, V., Sánchez-Guajardo, V., Catenaccio, A., Court, F., Pacheco, R. Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein. J. Vis. Exp. (185), e63313, doi:10.3791/63313 (2022).

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