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Biologia do Desenvolvimento

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用DMSO对人多能干细胞的暂时性治疗促进分化

JoVE Journal
Biologia do Desenvolvimento

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JoVE Journal Biologia do Desenvolvimento

Transient Treatment of Human Pluripotent Stem Cells with DMSO to Promote Differentiation

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用DMSO对人多能干细胞的暂时性治疗促进分化

DOI:

10.3791/59833-v

•

06:55 min

•

July 17, 2019

•

Danielle Sambo, Jingling Li, Thomas Brickler, Sundari Chetty²

¹Department of Psychiatry and Behavioral Sciences,Stanford University School of Medicine, ²Institute for Stem Cell Biology and Regenerative Medicine,Stanford University School of Medicine

Capítulos

00:04Título
01:232D Culture Differentiation
02:213D Culture Differentiation
03:28Ectoderm Differentiation
04:25Results: Effects of DMSO Pretreatment on Embryonic and Induced Pluripotent Stem Cell Differentiation
06:03Conclusion

Summary

Tadução automática

从人类多能干细胞(hPSCs)中产生分化的细胞类型具有巨大的治疗前景,但仍具有挑战性。PSC 通常表现出固有的无法区分,即使受到一组适当的信号刺激。此处介绍的一个简单的工具,用于增强各种 PSC 线路的多系差别。

Tags

Pluripotent Stem Cells DMSO Treatment Differentiation Priming Cell Replacement Therapy Disease Modeling Drug Screening 3D Culture Differentiation Cell Suspension

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