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JoVE Journal Genetics
Generation of Tumor Organoids from Genetically Engineered Mouse Models of Prostate Cancer
 

Generation of Tumor Organoids from Genetically Engineered Mouse Models of Prostate Cancer

Article DOI: 10.3791/59710-v • 08:54 min • June 13th, 2019
June 13th, 2019 •
1, 1, 1, 1
1Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center

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We show a method for necropsy and dissection of mouse prostate cancer models, focusing on prostate tumor dissection. A step-by-step protocol for generation of mouse prostate tumor organoids is also presented.

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Tumor Organoids Genetically Engineered Mouse Models Prostate Cancer In Vitro Cancer Research Drug Treatments En Bloc Extraction Male Mouse Urogenital System Testicle Dissection Bladder Elevation Urethra Incision Pelvic Lymph Nodes Rectum Grasp And Cut Metastatic Lesions Mesenteric Lymph Nodes Ilium Removal Duodenum Exposure Stomach Removal
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