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Generation of Tumor Organoids from Genetically Engineered Mouse Models of Prostate Cancer
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JoVE Journal Genetik
Generation of Tumor Organoids from Genetically Engineered Mouse Models of Prostate Cancer

Generation of Tumor Organoids from Genetically Engineered Mouse Models of Prostate Cancer

10,257 Views

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08:54 min

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June 13, 2019

DOI:

10.3791/59710-v

DOI:
10.3791/59710-v

•

08:54 min
June 13, 2019

•

6 Views
, , ,
1Department of Pharmacology & Therapeutics,Roswell Park Comprehensive Cancer Center

Summary

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We show a method for necropsy and dissection of mouse prostate cancer models, focusing on prostate tumor dissection. A step-by-step protocol for generation of mouse prostate tumor organoids is also presented.

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Tumor OrganoidsGenetically Engineered Mouse ModelsProstate Cancer3D Cell CultureIn Vitro Cancer ResearchMouse Urogenital SystemMetastatic LesionsLymph NodesOrgan Dissection

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Cite this Article

Wadosky, K. M., Wang, Y., Zhang, X., Goodrich, D. W. Generation of Tumor Organoids from Genetically Engineered Mouse Models of Prostate Cancer. J. Vis. Exp. (148), e59710, doi:10.3791/59710 (2019).

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