/
/
Delivery of Antibodies into the Murine Brain via Convection-enhanced Delivery
É necessária uma assinatura da JoVE para visualizar este conteúdo. Faça login ou comece sua avaliação gratuita.
Delivery of Antibodies into the Murine Brain via Convection-enhanced Delivery
8,009 Views
•
08:22 min
•
July 18, 2019
DOI:
Summary
Automatically generated
Convection-enhanced delivery (CED) is a method enabling effective delivery of therapeutics into the brain by direct perfusion of large tissue volumes. The procedure requires the use of catheters and an optimized injection procedure. This protocol describes a methodology for CED of an antibody into a mouse brain.
Read Article
Cite this Article
Beffinger, M., Schellhammer, L., Pantelyushin, S., vom Berg, J. Delivery of Antibodies into the Murine Brain via Convection-enhanced Delivery. J. Vis. Exp. (149), e59675, doi:10.3791/59675 (2019).
Copy