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A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton
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A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton
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05:47 min
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July 29, 2018
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In this protocol, we describe a micropipette method to directly apply a controlled force to the nucleus in a living cell. This assay allows interrogation of nuclear mechanical properties in the living, adherent cell.
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Zhang, Q., Tamashunas, A. C., Lele, T. P. A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton. J. Vis. Exp. (137), e58038, doi:10.3791/58038 (2018).
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