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A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton
JoVE Journal
生化学
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JoVE Journal 生化学
A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton

A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton

13,360 Views

05:47 min

July 29, 2018

DOI:

05:47 min
July 29, 2018

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概要

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In this protocol, we describe a micropipette method to directly apply a controlled force to the nucleus in a living cell. This assay allows interrogation of nuclear mechanical properties in the living, adherent cell.

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