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Γ-アミノ酪酸受容体をモジュレート新規化合物の探索の方法を入力、神経伝達
JoVE Journal
Neurociência
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JoVE Journal Neurociência
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Γ-アミノ酪酸受容体をモジュレート新規化合物の探索の方法を入力、神経伝達

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07:16 min

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August 16, 2018

DOI:

10.3791/57842-v

DOI:
10.3791/57842-v

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07:16 min
August 16, 2018

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7 Views
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1Discovery Neuroscience, Pharma Research and Early Development,Roche Innovation Center Basel, 2HiQScreen Sàrl 6

Summary

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ここでは、生理・薬理のバインドからの GABAAの受容器のアクティブな化合物を発見するためのプロトコルを提案する.

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Knoflach, F., Hernandez, M., Bertrand, D. Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission. J. Vis. Exp. (138), e57842, doi:10.3791/57842 (2018).

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