Journal
/
Bioengenharia
/
Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
JoVE Journal
Bioengenharia
This content is Free Access.
JoVE Journal Bioengenharia
Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery

12,161 Views

•

10:38 min

•

January 15, 2018

DOI:

10.3791/56760-v

DOI:
10.3791/56760-v

•

10:38 min
January 15, 2018

•

2 Views
, , , ,
1Department of Chemical Engineering,Northeastern University, 2Nanomedicine Science and Technology Center,Northeastern University, 3Department of Physics,Northeastern University, 4Departments of Bioengineering,Northeastern University, 5Department of Neuroscience,Albert Einstein College of Medicine

Summary

Automatically generated

We describe a method of synthesizing biocompatible 10-nm gold nanoparticles, functionalized by coating poly-ethylene glycol onto the surface. These particles can be used in vitro and in vivo for delivering therapeutics to nanoscale cellular and extracellular spaces that are difficult to access with conventional nanoparticle sizes.

Explore More Videos

Gold NanoparticlesPolymer CoatingFunctionalizationEndothelium TargetingDrug DeliveryBiocompatibilityFluorescence ImagingTHPCChloroauric AcidPEGDialysisLyophilization

Read Article

Cite this Article

Cheng, M. J., Prabakaran, P., Kumar, R., Sridhar, S., Ebong, E. E. Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery. J. Vis. Exp. (131), e56760, doi:10.3791/56760 (2018).

Download .ris file

Copy

Share Video

.

Copy