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Journal / Behavior / Signal Attenuation as a Rat Model of Obsessive…
JoVE Journal
Behavior

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JoVE Journal Behavior
Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
 

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Article DOI: 10.3791/52287-v • 09:29 min • January 9th, 2015
January 9th, 2015 •
*1, *1, *1, 1,2
1School of Psychological Sciences, Tel-Aviv University, 2Sagol School of Neuroscience, Tel-Aviv University
* These authors contributed equally

Capítulos

Resumo
Automatic Translation

The goal of the protocol described in this paper is to induce compulsive-like behavior in rats for the study of obsessive-compulsive disorder (OCD). This behavior is precipitated by attenuating a signal indicating that a lever-press response was effective in producing food.

Tags

Obsessive-compulsive Disorder OCD Signal Attenuation Rat Model Lever-pressing Feedback Cue Compulsive-like Behavior Extinction Validated Model Anti-compulsive Effects Pro-compulsive Effects Neural Substrate
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