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שושלת תכנות מחדש של תאי שמקורם בpericyte של המוח האנושי למבוגרים לנוירונים מושרה
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Neurociência
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JoVE Journal Neurociência
Lineage-reprogramming of Pericyte-derived Cells of the Adult Human Brain into Induced Neurons
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שושלת תכנות מחדש של תאי שמקורם בpericyte של המוח האנושי למבוגרים לנוירונים מושרה

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09:36 min

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May 12, 2014

DOI:

10.3791/51433-v

DOI:
10.3791/51433-v

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09:36 min
May 12, 2014

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1Department of Physiological Genomics, Institute of Physiology,Ludwig Maximilians University Munich, 2Tumor Biology Lab, Neurosurgical Clinic,Ludwig-Maximilians University Munich, 3Institut für Biochemie, Emil-Fischer-Zentrum,Friedrich-Alexander-Universität Erlangen-Nürnberg, 4Institute of Physiological Chemistry and Focus Program Translational Neuroscience,Johannes Gutenberg University Mainz

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Lineage-reprogrammingPericyteAdult Human BrainInduced NeuronsDirect ConversionNeurogenesisIn Vitro ModelingBrain RepairCerebral CortexPDGF Receptor-βCD146Sox2Ascl1Pericyte-derived Induced NeuronsPatch-clamp Recording

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Karow, M., Schichor, C., Beckervordersandforth, R., Berninger, B. Lineage-reprogramming of Pericyte-derived Cells of the Adult Human Brain into Induced Neurons. J. Vis. Exp. (87), e51433, doi:10.3791/51433 (2014).

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