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Criblage à haut débit pour à large spectre inhibiteurs chimiques de l'ARN virus

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Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

High-throughput Screening for Broad-spectrum Chemical Inhibitors of RNA Viruses

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Criblage à haut débit pour à large spectre inhibiteurs chimiques de l'ARN virus

13,463 Views

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11:34 min

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May 05, 2014

DOI:

10.3791/51222-v

DOI:

10.3791/51222-v

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11:34 min

May 05, 2014

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4 Views

Marianne Lucas-Hourani, Hélène Munier-Lehmann, Olivier Helynck, Anastassia Komarova, Philippe Desprès, Frédéric Tangy, Pierre-Olivier Vidalain

¹Unité de Génomique Virale et Vaccination, Virology Department,Institut Pasteur, CNRS UMR3569, ²Unité de Chimie et Biocatalyse, Biochemistry and Structural Biology Department,Institut Pasteur, CNRS UMR3523, ³Unité des Interactions Moléculaires Flavivirus-Hôtes, Virology Department,Institut Pasteur

Tags

High-throughput Screening Broad-spectrum Chemical Inhibitors RNA Viruses Cellular Pathways Host Cell Functions Antiviral Compounds Recombinant Viruses Reporter Enzymes Bioluminescence Luciferase Measles Virus Chikungunya Virus Cell Culture Assays

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