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In Vivo Modeling av Morbid Human Genome hjelp Danio rerio
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Biologia
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JoVE Journal Biologia
In Vivo Modeling of the Morbid Human Genome using Danio rerio

In Vivo Modeling av Morbid Human Genome hjelp Danio rerio

20,198 Views

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12:31 min

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August 24, 2013

DOI:

10.3791/50338-v

DOI:
10.3791/50338-v

•

12:31 min
August 24, 2013

•

4 Views
, , , , ,
1Center for Human Disease Modeling, Department of Cell Biology,Duke University Medical Center, 2Department of Evolutionary Anthropology,Duke University, 3Department of Pediatrics,Duke University Medical Center

Tags

ZebrafishIn Vivo ModelingHuman GenomeNonsynonymous ChangesComplementationMorpholinoMRNADevelopmental DefectsPediatric DiseaseAdult-onset DisordersOrthologousDominant NegativeGain Of FunctionLoss Of FunctionPhenotypingMorphogenetic SignalingCraniofacialCardiacVascularRenalSkeletal Muscle

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Niederriter, A. R., Davis, E. E., Golzio, C., Oh, E. C., Tsai, I., Katsanis, N. In Vivo Modeling of the Morbid Human Genome using Danio rerio. J. Vis. Exp. (78), e50338, doi:10.3791/50338 (2013).

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