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In Vivo Modeling of the Morbid Human Genome using Danio rerio
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Biologie
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Journal JoVE Biologie
In Vivo Modeling of the Morbid Human Genome using Danio rerio

In Vivo Modeling of the Morbid Human Genome using Danio rerio

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12:31 min

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August 24, 2013

DOI:

10.3791/50338-v

DOI:
10.3791/50338-v

•

12:31 min
August 24, 2013

•

4 Views
, , , , ,
1Center for Human Disease Modeling, Department of Cell Biology,Duke University Medical Center, 2Department of Evolutionary Anthropology,Duke University, 3Department of Pediatrics,Duke University Medical Center

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ZebrafishIn Vivo ModelingHuman GenomeNonsynonymous ChangesComplementationMorpholinoMRNADevelopmental DefectsPediatric DiseaseAdult-onset DisordersOrthologousDominant NegativeGain Of FunctionLoss Of FunctionPhenotypingMorphogenetic SignalingCraniofacialCardiacVascularRenalSkeletal Muscle

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Niederriter, A. R., Davis, E. E., Golzio, C., Oh, E. C., Tsai, I., Katsanis, N. In Vivo Modeling of the Morbid Human Genome using Danio rerio. J. Vis. Exp. (78), e50338, doi:10.3791/50338 (2013).

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