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Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique
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Biologia
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JoVE Journal Biologia
Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique

Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique

39,224 Views

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07:18 min

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October 27, 2011

DOI:

10.3791/3255-v

DOI:
10.3791/3255-v

•

07:18 min
October 27, 2011

•

2 Views
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1Department of Molecular Oncology, Weatherall Institute of Molecular Medicine,University of Oxford , 2Institute of Genetics and Biotechnology, Faculty of Biology,University of Warsaw

Tags

DNA ReplicationVisualizationVertebrate Model SystemDT40DNA Fiber TechniqueReplication Fork StabilityGenome DuplicationEndogenous DNA DamageExogenous DNA DamageGenomic InstabilityTumor DevelopmentFluorescence MicroscopyAvian B-cell Line DT40Protein FunctionReverse GeneticsDNA Replication And Genome StabilityReplication Fork DynamicsDNA Synthesis RateQualitative AnalysisDNA Fiber TechniqueHalogenated Nucleotides

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Schwab, R. A., Niedzwiedz, W. Visualization of DNA Replication in the Vertebrate Model System DT40 using the DNA Fiber Technique. J. Vis. Exp. (56), e3255, doi:10.3791/3255 (2011).

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