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Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
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JoVE Journal Medicina
Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis

16,799 Views

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06:03 min

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July 12, 2011

DOI:

10.3791/2737-v

DOI:
10.3791/2737-v

•

06:03 min
July 12, 2011

•

14 Views
, , , , ,
1Conrad Jobst Vascular Research Laboratories, Section of Vascular Surgery,University of Michigan , 2Department of Pharmacology,University of Michigan

Summary

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The electrolytic induction of endothelial activation to the internal surface of the Inferior Vena Cava results in venous type thrombus formation due to endothelial activation and partial blood stasis, two components of Virchow's triad.

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Diaz, J. A., Wrobleski, S. K., Hawley, A. E., Lucchesi, B. R., Wakefield, T. W., Myers, Jr., D. D. Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis. J. Vis. Exp. (53), e2737, doi:10.3791/2737 (2011).

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