Journal
/
医学
/
Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
JoVE 杂志
医学
This content is Free Access.
JoVE 杂志 医学
Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis

16,806 Views

•

06:03 min

•

July 12, 2011

DOI:

10.3791/2737-v

DOI:
10.3791/2737-v

•

06:03 min
July 12, 2011

•

14 Views
, , , , ,
1Conrad Jobst Vascular Research Laboratories, Section of Vascular Surgery,University of Michigan , 2Department of Pharmacology,University of Michigan

Summary

Automatically generated

The electrolytic induction of endothelial activation to the internal surface of the Inferior Vena Cava results in venous type thrombus formation due to endothelial activation and partial blood stasis, two components of Virchow's triad.

Explore More Videos

Electrolytic Inferior Vena Cava ModelEIMVenous ThrombosisAnimal ModelsDVT ResearchThrombus FormationThrombus ResolutionTherapeutic CompoundsPotential Therapeutic Antagonist CompoundsThrombosed VeinPartial StasisMajor VeinContinuous Blood FlowTherapeutic AgentsDynamic FashionSensitivityVenous Endothelial Cell ActivationLeukocyte MigrationVenous ThrombogenesisAnalytical Purposes

Read Article

Cite this Article

Diaz, J. A., Wrobleski, S. K., Hawley, A. E., Lucchesi, B. R., Wakefield, T. W., Myers, Jr., D. D. Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis. J. Vis. Exp. (53), e2737, doi:10.3791/2737 (2011).

Download .ris file

Copy

Share Video

.

Copy