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Detection of Post-translational Modifications on Native Intact Nucleosomes by ELISA
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Biologia
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JoVE Journal Biologia
Detection of Post-translational Modifications on Native Intact Nucleosomes by ELISA

Detection of Post-translational Modifications on Native Intact Nucleosomes by ELISA

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07:13 min

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April 26, 2011

DOI:

10.3791/2593-v

DOI:
10.3791/2593-v

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07:13 min
April 26, 2011

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, , , ,
1Institute for Stem Cell Biology and Regenerative Medicine,Stanford University , 2Department of Molecular and Cell Biology,University of Connecticut, 3Department of Pharmaceutical Sciences,University of Connecticut

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Post-translational ModificationsNative Intact NucleosomesELISAChromatinNucleosomeHistonesN-terminal TailsAcetylationMethylationPTMsEpigenetic Gene RegulationNucleosome ELISA (NU-ELISA)Global PTM SignaturesEpiproteomic State

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Dai, B., Dahmani, F., Cichocki, J. A., Swanson, L. C., Rasmussen, T. P. Detection of Post-translational Modifications on Native Intact Nucleosomes by ELISA. J. Vis. Exp. (50), e2593, doi:10.3791/2593 (2011).

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