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심정지, 소생술 및 자발순환 회복 후 심장 손상 및 혈역학을 연구하기 위한 새끼돼지 주산기 질식 모델
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January 13, 2023
DOI:
1Institute of Clinical Medicine, Faculty of Medicine,University of Oslo, 2Department of Neonatal Intensive Care, Division of Pediatric and Adolescent Medicine,Oslo University Hospital Rikshospitalet, 3Department of Pediatric Research, Division of Paediatric and Adolescent Medicine,Oslo University Hospital Rikshospitalet, 4Department of Pediatrics,Vestfold Hospital Trust, 5Department of Anesthesiology,Oslo University Hospital Rikshospitalet, 6Department of Pediatrics, Faculty of Medicine and Dentistry,University of Alberta, 7Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit,Royal Alexandra Hospital, 8Division of Paediatric and Adolescent Medicine, Institute of Clinical Medicine,University of Oslo, 9Department of Paediatrics and Adolescent Health,University of Botswana, 10Department of Pediatric Research, Oslo University Hospital,University of Oslo, 11Department of Pediatrics, Robert H Lurie Medical Research Center,Northwestern University Chicago
Summary
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이 새끼 돼지 모델에는 수술 기구, 심정지까지 질식, 소생술 및 소생술 후 관찰이 포함됩니다. 이 모델은 동물당 다중 샘플링을 허용하고 지속적인 침습적 동맥 혈압, ECG 및 비침습적 심박출량 모니터링을 사용하여 주산기 질식 및 신생아 심폐소생술에서 혈역학 및 심장 병태생리학에 대한 지식을 제공합니다.
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Keyword Extraction:Piglet Perinatal Asphyxia ModelCardiac InjuryHemodynamicsCardiac ArrestResuscitationReturn Of Spontaneous CirculationNeonatal Cardiopulmonary ResuscitationPulseless Electrical ActivitySurgical InterventionInternal Jugular VeinCentral Venous CatheterFentanyl IVBalanced Carbohydrate Electrolyte Solution
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Cite this Article
Stenersen, E. O., Olsen, A., Melheim, M., Solberg, R., Dannevig, I., Schmölzer, G., Cheung, P., Nakstad, B., Saugstad, O. D., Rønnestad, A., Solevåg, A. L. A Piglet Perinatal Asphyxia Model to Study Cardiac Injury and Hemodynamics after Cardiac Arrest, Resuscitation, and the Return of Spontaneous Circulation. J. Vis. Exp. (191), e64788, doi:10.3791/64788 (2023).
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