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Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
Chapters
- 00:05Introduction
- 00:57IRBP1-20-Complete Freund s Adjuvant (CFA) Emulsion Preparation and Injection
- 03:00Mouse Fundus Examination and Fluorescence Angiography
- 04:40Clinical Disease and Histological Scoring
- 06:06Results: Representative Fundoscopic, Histologic, and Fluorescence Imaging
- 06:59Conclusion
In this report we present a protocol that allows the investigator to generate a mouse model of intraocular uveitis. More commonly referred to as experimental autoimmune uveitis (EAU), this established model captures many aspects of human disease. Herein, we will describe how to induce and monitor disease progression using several readouts.
