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旋钮旋任务: 一种半自动评估大鼠前肢功能的方法
JoVE 신문
행동분석학
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JoVE 신문 행동분석학
The Knob Supination Task: A Semi-automated Method for Assessing Forelimb Function in Rats
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旋钮旋任务: 一种半自动评估大鼠前肢功能的方法

8,992 Views

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09:26 min

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September 28, 2017

DOI:

10.3791/56341-v

DOI:
10.3791/56341-v

•

09:26 min
September 28, 2017

•

1 Views
, , , , , , ,
1Burke Medical Research Institute, 2Texas Biomedical Center,The University of Texas at Dallas, 3Erik Jonsson School of Engineering and Computer Science,The University of Texas at Dallas, 4Brain and Mind Research Institute,Weill Cornell Medical College, 5Departments of Neurology and Pediatrics,Weill Cornell Medical College

Summary

Automatically generated

这份手稿描述了一个半自动的任务, 量化旋在大鼠。老鼠到达, 抓住, 并且 supinate 球形 manipulandum。如果转弯角度超过用户设定的标准, 老鼠就会得到一个小球的奖赏。与传统任务相比, 此任务增加了吞吐量、对伤害的敏感度和客观性。

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Cite this Article

Butensky, S. D., Bethea, T., Santos, J., Sindhurakar, A., Meyers, E., Sloan, A. M., Rennaker II, R. L., Carmel, J. B. The Knob Supination Task: A Semi-automated Method for Assessing Forelimb Function in Rats. J. Vis. Exp. (127), e56341, doi:10.3791/56341 (2017).

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