JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Chapters
- 00:00Title
- 01:31Establishing a Model of Acute Hyperglycemia in Zebrafish
- 02:59Establishing a Model of Chronic Hyperglycemia in Zebrafish
- 03:41Measuring Blood Glucose Levels in Zebrafish
- 05:00Analyzing Brain Cell Proliferation Following Hyperglycemia
- 06:24Sample Preparation for Immunohistochemistry
- 09:09Microscopy
- 10:05Studying the Impact of Hyperglycemia on Brain Repair Mechanism
- 11:08Imaging the Bio-distribution of Radiolabeled Molecules by PET-Scan
- 12:28Representative Results of [18F]-FDG PT/CT Imaging Distribution in Zebrafish
- 12:48Conclusion
Dit werk beschrijft methodes om acute en chronische hyperglycemie modellen in zebravis te bepalen. Het doel is om de invloed van hyperglycemie op fysiologische processen te onderzoeken, zoals constitutieve en schade-geïnduceerde neurogenese. Het werk benadrukt ook het gebruik van zebravis om radioactieve gelabelde moleculen te volgen (hier, [ 18 F] -FDG) met behulp van PET / CT.
