Alta resolução quantitativa Synaptic Proteome Profiling de rato regiões cerebrais Depois Auditivo Discriminação Aprendizagem

The identification of molecules and pathways controlling synaptic plasticity and memory is still a major challenge in neuroscience. Here, a workflow is described addressing the relative quantification of synaptic proteins supposedly involved in the molecular reorganization of synapses during learning and memory consolidation in an auditory learning paradigm.