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Ganglio espiral neurona explante cultura y Electrofisiología de multi electrodos matrices
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신경과학
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JoVE 신문 신경과학
Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays
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Ganglio espiral neurona explante cultura y Electrofisiología de multi electrodos matrices

9,530 Views

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07:51 min

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October 19, 2016

DOI:

10.3791/54538-v

DOI:
10.3791/54538-v

•

07:51 min
October 19, 2016

•

11 Views
, , , , ,
1Department of Otorhinolaryngology,Inselspital and University of Bern, 2Department of Clinical Research,Inselspital and University of Bern, 3Department of Physiology,University of Bern, 4Department of Clinical Neurosciences, Service ORL & HNS,University Hospital Geneva

Summary

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We present a protocol to culture primary murine spiral ganglion neuron explants on multi electrode arrays to study neuronal response profiles and optimize stimulation parameters. Such studies aim to improve the neuron-electrode interface of cochlear implants to benefit hearing in patients as well as the energy consumption of the device.

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Cite this Article

Hahnewald, S., Roccio, M., Tscherter, A., Streit, J., Ambett, R., Senn, P. Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays. J. Vis. Exp. (116), e54538, doi:10.3791/54538 (2016).

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