This protocol describes a technique to assess changes in the maternal vasculature during pregnancy in mice. Using stereological methods, remodeling of the decidual spiral arteries is assessed quantitatively and the results confirmed qualitatively using immunohistochemistry.
Kieckbusch, J., Gaynor, L. M., Colucci, F. Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus. J. Vis. Exp. (106), e53534, doi:10.3791/53534 (2015).