Traditional head fixation techniques have used metallic frames attached on the skull as an interface for head fixation apparatus. This protocol demonstrates a frameless, acrylic resin molding based head fixation technique for behavioral tasks in rodents.
Roh, M., Lee, K., Jang, I., Suk, K., Lee, M. Acrylic Resin Molding Based Head Fixation Technique in Rodents. J. Vis. Exp. (107), e53064, doi:10.3791/53064 (2016).