JoVE Journal
Medicine
Medicine
이 콘텐츠 오픈 액세스로 구독없이 시청하실 수 있습니다.
챕터
요약
In-depth analyses of cancer cell proteomes facilitate identification of novel drug targets and diagnostic biomarkers. We describe an experimental workflow for quantitative analysis of (phospho-)proteomes in cancer cell subpopulations derived from liquid and solid tumors. This is achieved by combining cellular enrichment strategies with quantitative Super-SILAC-based mass spectrometry.