De Mesenteriale Lymfe Duct gecanuleerde Rat Model: Toepassing op de beoordeling van Intestinal Lymfatische Drug Transport

Here we describe a technique to cannulate the mesenteric lymph duct in rats which enables quantification of lipid and drug transport via the lymphatic system following intestinal delivery. The technique can be adapted to assess mesenteric lymph concentrations and/or transport of fluid, immune cells, peptides, proteins and lipophilic molecules.