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녹농균 유발 폐 손상 모델
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면역학 및 감염병학
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JoVE 신문 면역학 및 감염병학
Pseudomonas aeruginosa Induced Lung Injury Model
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녹농균 유발 폐 손상 모델

18,202 Views

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07:24 min

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October 29, 2014

DOI:

10.3791/52044-v

DOI:
10.3791/52044-v

•

07:24 min
October 29, 2014

•

7 Views
, , , ,
1Department of Pharmacology, University of Illinois College of Medicine,University of Illinois at Chicago, 2Section of Pulmonary and Critical Care Medicine, Atlanta VAMC,Emory University, 3Biologic Resources Lab,University of Illinois at Chicago

Summary

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We have developed a mouse lung injury model by intra-tracheal injection of bacteria Pseudomonas aeruginosa. This model mimics lung injury during pneumonia and is clinically relevant.

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Pseudomonas AeruginosaLung InjuryMouse ModelAcute Lung InjuryPneumoniaInflammationAlveolar Epithelial BarrierCell DeathCell ProliferationRepair

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Cite this Article

Suresh Kumar, V., Sadikot, R. T., Purcell, J. E., Malik, A. B., Liu, Y. Pseudomonas aeruginosa Induced Lung Injury Model. J. Vis. Exp. (92), e52044, doi:10.3791/52044 (2014).

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