The present work illustrates the convenience of using sublingual immunotherapy to boost the innate immune response in the lungs and confer protection against acute pneumococcal pneumonia in mouse.
Muñoz-Wolf, N., Rial, A., Saavedra, J. M., Chabalgoity, J. A. Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections. J. Vis. Exp. (90), e52036, doi:10.3791/52036 (2014).