JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Protein silinmesi indüksiyonu yoluyla<em> In Utero</em> Elektroporasyon Transgenik Modelleri Nöronal Göç Açıkları tanımlayın
10,086 Views
•
12:01 min
•
January 12, 2015
DOI:
Summary
Automatically generated
Neuron migration is regulated by numerous cell autonomous and non-cell autonomous factors. This protocol shows how in utero electroporation can be used to determine whether a phenotype in a transgenic mouse is due to disruption of a cell intrinsic mechanism or impairment of interaction between the neuron and its environment.
Read Article
Cite this Article
Svoboda, D. S., Clark, A., Park, D. S., Slack, R. S. Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models. J. Vis. Exp. (95), e51983, doi:10.3791/51983 (2015).
Copy