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Farelerde Elektrofizyolojik Recordings Tasarım ve Ultralight Ağırlık Fabrikasyon, Ayarlanabilir Çoklu elektrot Probları
JoVE 신문
신경과학
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JoVE 신문 신경과학
Design and Fabrication of Ultralight Weight, Adjustable Multi-electrode Probes for Electrophysiological Recordings in Mice
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Farelerde Elektrofizyolojik Recordings Tasarım ve Ultralight Ağırlık Fabrikasyon, Ayarlanabilir Çoklu elektrot Probları

17,405 Views

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15:43 min

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September 08, 2014

DOI:

10.3791/51675-v

DOI:
10.3791/51675-v

•

15:43 min
September 08, 2014

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2 Views
, , , , , ,
1The Neuroscience Institute,New York University Langone Medical Center, 2Department of Brain and Cognitive Science,Massachusetts Institute of Technology

Summary

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Understanding the neural substrates of behavior requires brain circuit ensemble recording. Because of its genetic tractability, the mouse offers a model for circuit dissection and disease mimicry. Here, a method of designing and fabricating miniaturized probes is described that is suitable for targeting deep brain structure in the mouse.

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Cite this Article

Brunetti, P. M., Wimmer, R. D., Liang, L., Siegle, J. H., Voigts, J., Wilson, M., Halassa, M. M. Design and Fabrication of Ultralight Weight, Adjustable Multi-electrode Probes for Electrophysiological Recordings in Mice. J. Vis. Exp. (91), e51675, doi:10.3791/51675 (2014).

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