JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Barnes Maze Testing Strategies with Small and Large Rodent Models
Chapters
- 00:05Title
- 01:27Overview of the Barnes Maze for Small Rodents
- 02:58Running the Barnes Maze with Mice
- 05:50Setting up the Barnes maze for Rats Without Tracking
- 07:20Running the Barnes Maze with Rats
- 09:46Results: Maze Assessment of Polygamous and Monogamous Mice Fed Bisphenol A Supplemented Diets
- 12:23Conclusion
The dry-land Barnes maze is widely used to measure spatial navigation ability in response to mildly aversive stimuli. Over consecutive days, performance (e.g. latency to locate escape cage) of control subjects improves, indicative of normal learning and memory. Differences between rats and mice necessitate apparatus and methodology changes that are detailed here.
