Long Island University College of Veterinary Medicine 1 article published in JoVE Medicine An Effective Mouse Model of Unilateral Renal Ischemia-Reperfusion Injury José R. Godoy1, Grace Watson1, Carly Raspante1, Oscar Illanes1 1Department of Veterinary Biomedical Sciences, Long Island University College of Veterinary Medicine Renal ischemia-reperfusion injury is associated with high morbidity and mortality in hospitalized patients. Here, we present a simple and effective mouse model of unilateral renal ischemia-reperfusion injury and provide a sequential overview of representative pathological changes observed in the kidney.