Modeling Human Cerebellar Development <em>In Vitro</em> in 2D Structure

Deniz A. Madencioglu; Karina A. Kruth; Thomas H. Wassink; Vincent A. Magnotta; John A. Wemmie; Aislinn J. Williams

doi:10.3791/64462

Journal

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Neuroscience

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Modeling Human Cerebellar Development In Vitro in 2D Structure

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Modeling Human Cerebellar Development In Vitro in 2D Structure

Modeling Human Cerebellar Development In Vitro in 2D Structure

1,470 Views

•

06:14 min

•

September 16, 2022

DOI:

10.3791/64462-v

DOI:

10.3791/64462-v

•

06:14 min

September 16, 2022

•

1 Views

Deniz A. Madencioglu^1,3,4,5, Karina A. Kruth^1,3,4,5, Thomas H. Wassink^1,3, Vincent A. Magnotta^1,2,3,4,5, John A. Wemmie^1,3,4,5, Aislinn J. Williams^1,3,4,5

¹Department of Psychiatry,University of Iowa, ²Department of Radiology,University of Iowa, ³Carver College of Medicine,University of Iowa, ⁴Iowa Neuroscience Institute,University of Iowa, ⁵Pappajohn Biomedical Institute,University of Iowa

Summary

The present protocol explains the generation of a 2D monolayer of cerebellar cells from induced pluripotent stem cells for investigating the early stages of cerebellar development.

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Modeling Human Cerebellar Development In Vitro in 2D Structure

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