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Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

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12,347 Views

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12:54 min

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February 12, 2013

DOI:

10.3791/50018-v

DOI:
10.3791/50018-v

•

12:54 min
February 12, 2013

•

2 Views
, , , , ,
1Skaggs School of Pharmacy and Pharmaceutical Sciences,University of California, San Diego , 2Biomedical Sciences Program,University of California, San Diego , 3Department of Bioengineering,University of California, San Diego

Summary

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Here we describe a unique strategy for creating biocompatible, layered matrices with continuous interfaces between distinct layers for tissue engineering. Such a scaffold could provide an ideal customizable environment to modulate cell behavior by various biological, chemical or mechanical cues

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Cite this Article

Joshi-Barr, S., Karpiak, J. V., Ner, Y., Wen, J. H., Engler, A. J., Almutairi, A. Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering. J. Vis. Exp. (72), e50018, doi:10.3791/50018 (2013).

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