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Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
Journal JoVE
Bio-ingénierie
This content is Free Access.
Journal JoVE Bio-ingénierie
Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
DOI:

12:54 min

February 12, 2013

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Chapitres

  • 00:05Titre
  • 02:17Synthesis of Fluorescently Labeled Acryloyl-PEG-RGDS
  • 05:14Fabrication of 2-D Molds
  • 06:39Fabrication of PEG Gel with Alternating RGDS-Alexa 350 Layer
  • 09:472-D Cell Culture of C2C12 Myoblasts on DGMP Gels
  • 11:15Results: DGMP Gels can Vary Properties to Analyze Cellular Attachment and Growth
  • 12:02Conclusion

Summary

Traduction automatique

Here we describe a unique strategy for creating biocompatible, layered matrices with continuous interfaces between distinct layers for tissue engineering. Such a scaffold could provide an ideal customizable environment to modulate cell behavior by various biological, chemical or mechanical cues

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