/
/
Expanding Cytotoxic T Lymphocytes from Umbilical Cord Blood that Target Cytomegalovirus, Epstein-Barr Virus, and Adenovirus
A subscription to JoVE is required to view this content. Sign in or start your free trial.
12,616 Views
•
11:18 min
•
May 07, 2012
DOI:
1Center for Cell and Gene Therapy,Baylor College of Medicine , 2Pathology and Immunology,Baylor College of Medicine , 3Department of Stem Cell Transplantation and Cellular Therapy,University of Texas M.D. Anderson Cancer Center, 4Medicine,Baylor College of Medicine , 5Department of Pediatrics,Baylor College of Medicine
Summary
Automatically generated
Here we describe the first good manufacturing practice (GMP)-compliant method of producing virus-specific cytotoxic T lymphocytes (CTL) from umbilical cord blood, a source of predominantly naîve T cells.
Read Article
Cite this Article
Hanley, P. J., Lam, S., Shpall, E. J., Bollard, C. M. Expanding Cytotoxic T Lymphocytes from Umbilical Cord Blood that Target Cytomegalovirus, Epstein-Barr Virus, and Adenovirus. J. Vis. Exp. (63), e3627, doi:10.3791/3627 (2012).
Copy