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A Comprehensive Protocol for Delivering Intrathecal Injections in Neonatal Mice
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Author Spotlight: Intrathecal Injection – An Efficient and Reliable Delivery Method to Test the Efficacy of Gene Editing in Neonatal Mouse Brains
JoVE Journal
神経科学
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JoVE Journal 神経科学
Intrathecal Injection of Newborn Mouse for Genome Editing and Drug Delivery

Author Spotlight: Intrathecal Injection – An Efficient and Reliable Delivery Method to Test the Efficacy of Gene Editing in Neonatal Mouse Brains

1,537 Views

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02:09 min

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March 08, 2024

DOI:

10.3791/65761-v

DOI:
10.3791/65761-v

•

02:09 min
March 08, 2024

•

45 Views
,
1遺伝学科,Yale University School of Medicine, 2神経科学科,Yale University School of Medicine, 3小児科,Yale University School of Medicine

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Intrathecal InjectionNewborn MouseGenome EditingDrug DeliveryNeurodevelopmental DisorderGene EditingCentral Nervous SystemCerebrospinal FluidPreclinical StudiesNeurobehavioral AnalysisIPSCICV InjectionNon-viralNon-nanoparticle

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Lu, X., Jiang, Y. Intrathecal Injection of Newborn Mouse for Genome Editing and Drug Delivery. J. Vis. Exp. (205), e65761, doi:10.3791/65761 (2024).

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