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A Comprehensive Protocol for Delivering Intrathecal Injections in Neonatal Mice

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Author Spotlight: Intrathecal Injection – An Efficient and Reliable Delivery Method to Test the Efficacy of Gene Editing in Neonatal Mouse Brains

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JoVE 杂志神经科学

Intrathecal Injection of Newborn Mouse for Genome Editing and Drug Delivery

Author Spotlight: Intrathecal Injection – An Efficient and Reliable Delivery Method to Test the Efficacy of Gene Editing in Neonatal Mouse Brains

A Comprehensive Protocol for Delivering Intrathecal Injections in Neonatal Mice

DOI:

10.3791/65761-v

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02:09 min

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March 08, 2024

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Xiaona Lu, Yong-hui Jiang^2,3

¹Department of Genetics,Yale University School of Medicine, ²Department of Neuroscience,Yale University School of Medicine, ³Department of Pediatrics,Yale University School of Medicine

Tags

Intrathecal Injection Newborn Mouse Genome Editing Drug Delivery Neurodevelopmental Disorder Gene Editing Central Nervous System Cerebrospinal Fluid Preclinical Studies Neurobehavioral Analysis IPSC ICV Injection Non-viral Non-nanoparticle

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Author Spotlight: Intrathecal Injection – An Efficient and Reliable Delivery Method to Test the Efficacy of Gene Editing in Neonatal Mouse Brains

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