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免疫学と感染
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Screening of β2 Integrin Activation Inhibitors in Human Neutrophils
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Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation
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JoVE Journal 免疫学と感染
A Flow Cytometry-Based High-Throughput Technique for Screening Integrin-Inhibitory Drugs

Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation

Screening of β2 Integrin Activation Inhibitors in Human Neutrophils

DOI:
10.3791/64401-v

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00:45 min

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February 02, 2024

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, , , ,
1Department of Immunology, School of Medicine,UConn Health, 2Center for Molecular Discovery,University of New Mexico Health Sciences Center, 3Comprehensive Cancer Center,University of New Mexico Health Sciences Center, 4病理学科,University of New Mexico Health Sciences Center, 5Autophagy, Inflammation, & Metabolism (AIM) Center,University of New Mexico

タグ

Flow CytometryHigh-throughput ScreeningIntegrin InhibitorBeta-2 IntegrinNeutrophilAnti-inflammatoryConformational Change AntibodyFMLPGPCR

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Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation

High-Throughput Screening of Compounds Using Neutrophils Isolated from Human Blood in a 384-Well Plate Format

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