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Journal
/
Immunology and Infection
/
Screening of β2 Integrin Activation Inhibitors in Human Neutrophils
/
Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation
JoVE Journal
Immunology and Infection
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JoVE Journal
Immunology and Infection
A Flow Cytometry-Based High-Throughput Technique for Screening Integrin-Inhibitory Drugs
Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation
Screening of β2 Integrin Activation Inhibitors in Human Neutrophils
DOI:
10.3791/64401-v
•
00:45 min
•
February 02, 2024
•
Ziming Cao
,
Matthew J. Garcia
,
Larry A. Sklar
3,4,5
,
Angela Wandinger-Ness
4
,
Zhichao Fan
1
Department of Immunology, School of Medicine
,
UConn Health
,
2
Center for Molecular Discovery
,
University of New Mexico Health Sciences Center
,
3
Comprehensive Cancer Center
,
University of New Mexico Health Sciences Center
,
4
Department of Pathology
,
University of New Mexico Health Sciences Center
,
5
Autophagy, Inflammation, & Metabolism (AIM) Center
,
University of New Mexico
Tags
Flow Cytometry
High-throughput Screening
Integrin Inhibitor
Beta-2 Integrin
Neutrophil
Anti-inflammatory
Conformational Change Antibody
FMLP
GPCR
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Author Spotlight: Development of a Method for Identifying Small Molecular Antagonists of β2 Integrin Activation
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