S1P exerts its diverse physiological effects through the S1P receptors (S1PRs) subfamily. Here, a pipeline is described to expound on the structures and function of S1PRs.
Cheng, L., Su, L., Tian, X., Xia, F., Zhao, C., Yan, W., Shao, Z. A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors. J. Vis. Exp. (184), e64054, doi:10.3791/64054 (2022).