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CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells
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CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells

CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells

2,246 Views

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12:14 min

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June 02, 2022

DOI:

10.3791/64025-v

DOI:
10.3791/64025-v

•

12:14 min
June 02, 2022

•

12 Views
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1Umeå Centre for Molecular Medicine,Umeå University, 2Department of Histology and Embryology, Medical Academy,Lithuanian University of Health Sciences

概要

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The CAM-Delam assay to evaluate the metastatic capacity of cancer cells is relatively fast, easy, and cheap. The method can be used for unraveling the molecular mechanisms regulating metastasis formation and for drug screening. An optimized assay for analyzing human tumor samples could be a clinical method for personalized cancer treatment.

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Cite this Article

Green, T., Šlekienė, L., Gunhaga, L. CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells. J. Vis. Exp. (184), e64025, doi:10.3791/64025 (2022).

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