Journal
/
癌症研究
/
CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells
JoVE 杂志
癌症研究
Author Produced
This content is Free Access.
JoVE 杂志 癌症研究
CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells

CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells

2,288 Views

•

12:14 min

•

June 02, 2022

DOI:

10.3791/64025-v

DOI:
10.3791/64025-v

•

12:14 min
June 02, 2022

•

12 Views
, ,
1Umeå Centre for Molecular Medicine,Umeå University, 2Department of Histology and Embryology, Medical Academy,Lithuanian University of Health Sciences

Summary

Automatically generated

The CAM-Delam assay to evaluate the metastatic capacity of cancer cells is relatively fast, easy, and cheap. The method can be used for unraveling the molecular mechanisms regulating metastasis formation and for drug screening. An optimized assay for analyzing human tumor samples could be a clinical method for personalized cancer treatment.

Explore More Videos

CAM-Delam AssayMetastatic PropertiesDelaminationInvasion CapacityCancer CellsMetastatic AggressivenessChick EmbryoEgg IncubationSilicone RingsCollagen RPMI MixCancer Cell CultureTrypsinization

Read Article

Cite this Article

Green, T., Šlekienė, L., Gunhaga, L. CAM-Delam Assay to Score Metastatic Properties by Quantifying Delamination and Invasion Capacity of Cancer Cells. J. Vis. Exp. (184), e64025, doi:10.3791/64025 (2022).

Download .ris file

Copy

Share Video

.

Copy