Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae

Kazuhide Asakawa; Hiroshi Handa; Koichi Kawakami

doi:10.3791/62932

ジャーナル

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神経科学

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Optogenetische faseovergang van TDP-43 in spinale motorneuronen van zebravislarven

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神経科学

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JoVE Journal 神経科学

Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae

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Optogenetische faseovergang van TDP-43 in spinale motorneuronen van zebravislarven

5,742 Views

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07:14 min

•

February 25, 2022

DOI:

10.3791/62932-v

DOI:

10.3791/62932-v

•

07:14 min

February 25, 2022

•

3 Views

Kazuhide Asakawa¹, Hiroshi Handa¹, Koichi Kawakami^2,3

¹Department of Chemical Biology,Tokyo Medical University, ²Division of Molecular and Developmental Biology,National Institute of Genetics, ³遺伝学科,Graduate University for Advanced Studies (SOKENDAI)

概要

We beschrijven een protocol om faseovergang van TAR DNA-bindend eiwit 43 (TDP-43) te induceren door licht in de spinale motorneuronen met zebravissen als model.

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Optogenetische faseovergang van TDP-43 in spinale motorneuronen van zebravislarven

概要

Automatically generated

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