Presented here is a protocol for the recording of muscle velocity recovery cycles (MVRCs), a new method of examining muscle membrane properties. MVRCs enable in vivo assessment of muscle membrane potential and alterations in muscle ion channel function in relation to pathology, and it enables the demonstration of muscle depolarization in neurogenic muscles.
Witt, A., Bostock, H., Z'Graggen, W. J., Tan, S. V., Kristensen, A. G., Kristensen, R. S., Larsen, L. H., Zeppelin, Z., Tankisi, H. Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties. J. Vis. Exp. (156), e60788, doi:10.3791/60788 (2020).