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Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties
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08:27 min
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February 19, 2020
DOI:
1Department of Clinical Neurophysiology,Aarhus University Hospital, 2UCL Queen Square Institute of Neurology, Queen Square House, 3Departments of Neurology and Neurosurgery, Inselspital, Bern University Hospital,University of Bern, 4MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology,The National Hospital for Neurology and Neurosurgery
Summary
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Presented here is a protocol for the recording of muscle velocity recovery cycles (MVRCs), a new method of examining muscle membrane properties. MVRCs enable in vivo assessment of muscle membrane potential and alterations in muscle ion channel function in relation to pathology, and it enables the demonstration of muscle depolarization in neurogenic muscles.
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Witt, A., Bostock, H., Z'Graggen, W. J., Tan, S. V., Kristensen, A. G., Kristensen, R. S., Larsen, L. H., Zeppelin, Z., Tankisi, H. Muscle Velocity Recovery Cycles to Examine Muscle Membrane Properties. J. Vis. Exp. (156), e60788, doi:10.3791/60788 (2020).
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